Collect all Trophies
Exit the Medical Healing Suites
Destroy the Medical CPU Nodes
Deploy Isotope X-22 and enable the Radiation Shields
Disable the Safety Override for the Mining Laser
Destroy the Mining Laser
Defeat Edward Diego
Replace Interface Demodulator and fix Subsystem Relay 428
Jettison Beta Grove on the Executive level
Destroy the Antenna Relays on the Systems Engineering Level
Start the Reactor Self-Destruct Countdown
Kill Edward Diego
Destroy the Cyber Core in each Cyberspace level
Use the Isolinear Chipset
Defeat SHODAN
Use every type of Dermal Patch
Recharge 20 times at a Power Station
Consume 30 Food and Drink items
Salvage 100 Junk Items at Salvage Stations
Acquire a Laser Rapier
Discover all Firearms
Find and install every Weapon Modkit
Find the final version of all Hardware Attachments
Purchase 10 ammunition items from Ammo Depots
Purchase a grenade from a vending machine
Solve 15 Circuit or Wire Panels without using a Logic Probe
Hack 20 enemies which have been acquired by the Target ID Hardware
Kill an enemy by bouncing a shot from the Ion Rifle
Kill two or more enemies with a single Plasma Core
Kill two or more enemies with a single Railgun Projectile
Kill an enemy with an Overhead Monitor
Kill 10 enemies while under the effect of the Berserk Combat Booster
Kill three or more enemies with a single explosive weapon
Defeat Edward Diego while en route to the Life Pods
Kill Edward Diego with the Laser Rapier
Defeat all of the Cortex Reavers on Citadel Station
Destroy all of SHODAN’s cameras and CPU Nodes
Find all Audio Logs and Data Sticks on Citadel Station
Complete the game on any difficulty
Complete the game on the highest difficulties
Discover a hidden door
Jump across the big ramp in the Storage level
Solve the Chess Puzzle in Delta Grove
Find the hidden Wrench
Find the hidden Audio Log
Find Skully, the Nightdive skull, on every level